It is difficult to reproduce physiological conditions in a simple Petri dish. Reproducing culture conditions of intestinal cells requires a complex three-dimensional environment. To be able to study their growth, researchers from LAAS-CNRS and Arnaud Besson's team from LBCMCP are printing high-resolution 3D culture scaffolds. Published in the journal Biomaterials, this work shows that cells grown on these 3D culture models behave in a similar way to intestinal cells.
Justine Creff, Rémi Courson, Thomas Mangeat, Julie Foncy, Sandrine Souleille, C. Thibault, Arnaud Besson, Laurent Malaquin.
Fabrication of 3D scaffolds reproducing intestinal epithelium topography by high-resolution 3D stereolithography.
Biomaterials, Volume 221, November 2019, 119404. https://doi.org/10.1016/j.biomaterials.2019.119404