Cell-cell communication in the mammalian nervous system

Alice DAVY


DR CNRS
05 61 55 75 51

Team members

  Researcher
  • Catherine LECLERC
  • Marc MOREAU
  • Isabelle NEANT
  Technical staff
  • Christophe AUDOUARD
  • Thomas JUNGAS
  Postdoc
  • Caroline BADOUEL
  • Mohamad-Ali FAWAL
  PhD
  • Anthony KISCHEL

Presentation

Research in the team focuses on elucidating mechanisms that govern development of the nervous system and how genetic alterations of this complex developmental program may lead to brain disease in the adult. 
We investigate cell-to-cell communication via the Eph/ephrin signaling pathway, mostly in the context of neurogenesis and neural progenitor specification and maintenance. Our studies combine in vivo experimentations on genetic mouse models, ex vivo experimentations on tissue explants and in vitro cultures of primary neural progenitors, brain tumor stem cells and cell lines.  

Projets

Elaborating a theoretical framework of neocortex development

Exploring parallels between neural progenitors and brain tumor stem cells

Investigating specification of neural progenitor fates

Publications

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Funding

     

prestige

Alumni

LAUSSU Julien (PhD 2011-2015)> postdoc CRBM, Montpellier, France

ARVANITIS Constandina (postdoc 2007-2010, CR1 2010-2014)> I2MC, Toulouse

LUXEY Maëva (PhD 2007-2011)> postdoc IRCM, Montréal, Canada

BEHAR Annie, AI (CDD 2008-2010)

Université Paul Sabatier
118 Route de Narbonne

31062 TOULOUSE Cedex
France

Annuaire général