Currently, there is no efficient targeted therapy that can prevent the metastatic dissemination of triple-negative breast cancer (TNBC). Our recent work identified PKCÎ¸ as a potential new marker of TNBC and as a strong inducer of cancer invasion. PKCÎ¸ is well known for its role in the immune system. However, the link between PKCÎ¸ and cancer is extremely limited. Our project is to understand how PKCÎ¸ controls the cancer invasion. To determine the detailed mechanism of this control, we are using cancer cells and mouse models.
Other funding : ATIP-Avenir