Control of cancer invasion by the novel PKCtheta

Intervenants

  • Xiaobo WANG
  • Karine BELGUISE
  • Valérie CADAMURO
  • Jiaying LIU
  • Lucie CHADELLE

Currently, there is no efficient targeted therapy that can prevent the metastatic dissemination of triple-negative breast cancer (TNBC). Our recent work identified PKCθ as a potential new marker of TNBC and as a strong inducer of cancer invasion. PKCθ is well known for its role in the immune system. However, the link between PKCθ and cancer is extremely limited. Our project is to understand how PKCθ controls the cancer invasion. To determine the detailed mechanism of this control, we are using cancer cells and mouse models.

Funding

Other funding : ATIP-Avenir

Université Paul Sabatier
118 Route de Narbonne

31062 TOULOUSE Cedex
France

Annuaire général