Claire Rampon

Présentation

Main research interests

My research aims to characterize cerebral plasticity underlying learning and memory functions in the healthy brain and in mouse models of Alzheimer's disease. In particular, i want to understand the role played by adult-generated hippocampal neurons in memory formation. We recently started investigating how endogenous neural stem cells from the diseased adult brain may be manipulated to become fully functional neurons able to drive cognitive rehabilitation.

 

Sponsors:  ANR, France Alzheimer's association, Fondation pour la Recherche sur le Cerveau, Cifre, CNRS, UPS

 

 

Publications

• Arrázola MS, Andraini T, Szelechowski M, Mouledous L, Arnauné-Pelloquin L, Davezac N, Belenguer P, Rampon C, Miquel MC.
  Mitochondria in developmental and adult neurogenesis
  Neurotox Res. 2019;36(2):257-267. doi: 10.1007/s12640-018-9942-y
  2018 Aug
• Bétourné A, Szelechowski M, Thouard A, Abrial E, Jean A, Zaidi F, Foret C, Bonnaud EM, Charlier CM, Suberbielle E, Malnou CE, Granon S, Rampon C, Gonzalez-Dunia D..
  Hippocampal expression of a virus-derived protein impairs memory in mice.
  Proc Natl Acad Sci U S A. 2018;115(7):1611-1616. doi: 10.1073/pnas.1711977115
  2018 Feb
• Richetin K, Petsophonsakul P, Roybon L, Guiard BP, Rampon C.
  Differential alteration of hippocampal function and plasticity in females and males of the APPxPS1 mouse model of Alzheimer’s disease
  Neurobiol Aging. 2017;57:220-231. doi: 10.1016/j.neurobiolaging.2017.05.025
  2017 Jun
• Petsophonsakul P, Richetin K, Andraini T, Roybon L, Rampon C.
  Memory formation orchestrates the wiring of adult-born hippocampal neurons into brain circuits
  Brain Struct Funct. 2017;222(6):2585-2601. doi: 10.1007/s00429-016-1359-x
  2017 Jan
• Bezzina C, Verret L, Halley H, Dahan L*, Rampon C*. .
  Environmental enrichment does not influence hypersynchronous network activity in the Tg2576 mouse model of Alzheimer’s disease.
  Front. Aging Neurosci 7:178.
  2015 Sep

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