As a lecturer and researcher at the University of Toulouse, I teach genetics in the Life Sciences program.
The common thread running through my scientific career has been understanding the mechanisms that maintain genome stability. After completing a PhD on the study of DNA polymerase Theta in genomic replication (CRCT, Toulouse), I focused my research on another pillar of genomic integrity maintenance: DNA damage repair. During my first postdoctoral fellowship in JY Masson's team in Quebec City, I identified a new player in the DNA crosslink repair pathway using a whole genome CRISPR-CAS9 screen strategy. I then joined G Legube's team (CBI, Toulouse), whose work focuses on the repair of DNA double-strand breaks in active regions of the genome.
Today, as part of Didier Trouche's team, my project aims at identifying the potential link between histone H2A.Z variants and the Fanconi anemia repair pathway, mainly described in DNA crosslink repair.