Hussein HAMZE | CBI Toulouse

HAMZE

Hussein

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EUKARYBIO Biogenesis of Eukaryotic Ribosomes

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05 61 33 59 53

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Currently in the 4th year of my PhD, in Molecular Genetics at Toulouse III University, entitled "Structural and functional study of the early stages of eukaryotic large ribosomal subunit synthesis in the yeast Saccharomyces cerevisiae".
Eukaribio team, MCD-CBI laboratory, CNRS/Université Toulouse III.

Master 2 Research: Genes, Cells and Development (2021)
Paul Sabatier University - Toulouse III - France
Overall average: 16.32 / 20 Honors: Very Good Ranking: 3 / 12

Master 1 Research - Genetics, Genomics and Biotechnology GGB (2020)
University of Western Brittany - Brest - France

Master 1 Research - Animal Biology (2019)
Lebanese University - Faculty of Sciences - Section (I) - Lebanon
Honors: Good

Publications:

Hamze H, Jaafar M, Khreiss A, Dominique C, Bourdeaux J, Santo PE, Méndez-Godoy A, Kressler D, Humbert O, Plisson-Chastang C, Albert B, Henras AK, Henry Y. The snoRNP chaperone snR190 and the Npa1 complex form a macromolecular assembly required for 60S ribosomal subunit maturation. Nucleic Acids Res. 2025 Feb. doi: 10.1093/nar/gkaf134.

Dominique C, Maiga NK, Méndez-Godoy A, Pillet B, Hamze H, Léger-Silvestre I, Henry Y, Marchand V, Gomes Neto V, Dez C, Motorin Y, Kressler D, Gadal O, Henras AK, Albert B. The dual life of disordered lysine-rich domains of snoRNPs in rRNA modification and nucleolar compaction. Nat Commun. 2024 Oct. doi: 10.1038/s41467-024-53805-1.

Mitterer V, Hamze H, Kunowska N, Stelzl U, Henras AK, Hurt E. The RNA helicase Dbp10 coordinates assembly factor association with PTC maturation during ribosome biogenesis. Nucleic Acids Res. 2024 Feb. doi: 10.1093/nar/gkad1206.

Actuellement en 4ème année de thèse, en Génétique Moléculaire à l’université Toulouse III, intitulée Étude structurale et fonctionnelle des étapes précoces de la synthèse de la grande sous-unité ribosomique eucaryote chez la levure Saccharomyces cerevisiae
Équipe Eukaribio, laboratoire MCD-CBI, CNRS/Université Toulouse III.

Master 2 Recherche: Gènes, Cellules et Développement (2021)
Université Paul Sabatier – Toulouse III – France
Moyenne Générale : 16.32 / 20 Mention : Très Bien Classement : 3 / 12

Master 1 Recherche - Génétique, Génomique et Biotechnologie GGB (2020)
Université de Bretagne Occidentale – Brest – France

Master 1 Recherche - Biologie animale (2019)
Université Libanaise – Faculté des sciences – Section (I) – Liban
Mention : Bien

Publications:

Hamze H, Jaafar M, Khreiss A, Dominique C, Bourdeaux J, Santo PE, Méndez-Godoy A, Kressler D, Humbert O, Plisson-Chastang C, Albert B, Henras AK, Henry Y. The snoRNP chaperone snR190 and the Npa1 complex form a macromolecular assembly required for 60S ribosomal subunit maturation. Nucleic Acids Res. 2025 Feb. doi: 10.1093/nar/gkaf134.

Dominique C, Maiga NK, Méndez-Godoy A, Pillet B, Hamze H, Léger-Silvestre I, Henry Y, Marchand V, Gomes Neto V, Dez C, Motorin Y, Kressler D, Gadal O, Henras AK, Albert B. The dual life of disordered lysine-rich domains of snoRNPs in rRNA modification and nucleolar compaction. Nat Commun. 2024 Oct. doi: 10.1038/s41467-024-53805-1.

Mitterer V, Hamze H, Kunowska N, Stelzl U, Henras AK, Hurt E. The RNA helicase Dbp10 coordinates assembly factor association with PTC maturation during ribosome biogenesis. Nucleic Acids Res. 2024 Feb. doi: 10.1093/nar/gkad1206.