Presentation
Many CBI projects are developed in partnership with industrial players. Our scientific advances are assessed in terms of patentability, potential therapeutic applications and industrial or commercial exploitation.
Jérôme Castandet, our Business Developer is involved in developing industrial partnerships, through service provision, research collaborations and Laboratoires Communs (LabCom). These activities are carried out in close collaboration with Partnerships and Valorisation Department (SPV) of the CNRS Occitanie Ouest Regional Delegation (DR14), CNRS Innovation, the CNRS Technology Transfer Office, Toulouse Tech Transfer (TTT), la Société d’Accélération du Transfert de Technologies (SATT) of Toulouse and the CNRS Ingénieurs Transfert national program.
In 2024, the CNRS LabCom Trans NMDA was established between Rest Therapeutics and three CNRS laboratories – CBI-CRCA (for in vivo biology), IPBS (for in vitro biology) and LHFA (for chemistry) – to develop translational research programs targeting the NMDA glutamate receptor family.
CBI has built numerous research collaborations and service agreements with industrial partners such as Enterosys, Eurofins Calixar, Gataca Systems, Humana Biosciences, Inscoper, Koppert, LabSoft, Mibelle Group Biochemistry, NeoVirTech, Oxxius, Phodé, Pierre Fabre and ReST Therapeutics.
Through the Business Developer, CBI works closely with CNRS Innovation and Toulouse Tech Transfer (TTT), focused on accelerating innovation through technology transfer and the creation of start-ups, in order to:
– Identify projects and results from laboratories with high potential of valorization
– Invest in inventions with significant societal impact, providing support for proof-of-concept and prototype development to attract industrial interest
– Protect innovations through patent filing
Since 2021, two TTT pre-maturation grants have been awarded to the laboratory (Drs. S. Lebaron et T. Mangeat).
One patent (Dr. T. Mangeat) based on RIM technology developed at the CBI has been filed.
In 2024, two invention disclosure statements from projects developed at the CBI have been filed with TTT and are currently under evaluation (Drs. F. Escaffit et M. Carraz in collaboration with Institut de Recherche pour le Développement : IRD).
TTT also facilitates the transfer of these inventions to companies through licensing and supports start-up creation.
In 2014, the NeoVirTech company was created on the basis of research carried out in Dr. K. Bystricky’s team at CBI-MCD.
Resulting from CBI research and work carried out on the LITC microscopy platform, the RIMEO start-up creation project which makes it possible to obtain high-resolution images with low-resolution microscopes is currently in progress by Dr. S. Labouesse.
Each year, CBI supports several doctoral students through the CIFRE program (Convention Industrielle de Formation par la Recherche). This program fosters public-private research partnerships by co-financing the training of doctoral students hired by a company. The research mission assigned to these students aligns with the company’s R&D strategy and is conducted in collaboration with an academic laboratory. In 2024, three CIFRE thesis are in progress at the laboratory (directed by Dr. M. Chavent with Eurofins Calixar, Dr. B. Guiard with Phodé and Dr. C. Pasquaretta with Colomiers Rugby).
CBI has built numerous research collaborations, service provisions and Laboratoire Commun (LabCom) with industrial partners such as Enterosys, Eurofins Calixar, Gataca Systems, Humana Biosciences, Inscoper, Koppert, LabSoft, Mibelle Group Biochemistry, NeoVirTech, Oxxius, Phodé, Pierre Fabre and ReST Therapeutics.
We collaborated with the MBC platform of the CBI on R&D projects related to stress-related behaviors in a depression model. Their expertise and scientific rigor have significantly contributed to our progress. We highly recommend CBI for their professionalism, adaptability, and commitment to scientific excellence.
Anne ABOT, CSO chez Enterosys
As a recognized expert in super-resolution imaging, GATACA SYSTEMS is proud to collaborate closely with CBI on innovative technological projects as an industrial partner. This relationship is driven by our shared commitment to advancing imaging technologies in a meaningful and impactful way. We are highly motivated and, above all, excited to actively contribute to the creation and expansion of new frontiers in molecular biology research.
Erwann MAURIER, Sales Director at GATACA SYSTEMS
Our collaboration with the Image Analysis service at CBI has enabled us to develop a dedicated software tool for quantifying the beating frequency of cilia in epithelial cells of the human respiratory system.
Stefano PALEA, CEO of Humana Biosciences
For several years, Inscoper has been collaborating with Thomas Mangeat on his innovative developments in microscopy imaging. His projects provide our company with the opportunity to be involved in highly advanced and innovative solutions for biomedical research, often with significant challenges in software development and system control, our area of expertise.
Otmane BOUCHAREB, CEO INSCOPER
At NeoVirTech, we had a project aimed at visualizing viral infection and replication in living cells using ANCHOR technology. After several proof-of-concept studies, we wanted to verify whether the viral genome position we observed in live cells accurately corresponded to that of the viral DNA and capsid inside the cell. The only way to confirm this was through correlative electron-fluorescence microscopy, a field in which we had no expertise. We worked closely with METI, the electron microscopy platform at CBI (Stéphanie Balor) to successfully carry out this study. They quickly understood our needs and conducted the necessary experiments, validating our ability to visualize viruses in living cells. This work was published in the Journal of Virology.
Franck GALLARDO, CEO NeoVirTech
Oxxius is proud to maintain a long-standing partnership with LITC. Over the years, their expertise and collaborative approach have enabled us to develop pioneering solutions in our field. We extend our special thanks to Thomas Mangeat’s team, where innovation never stops. We look forward to continuing this great collaboration and exploring new possibilities together.
Florestan ROUME, Regional Sales Manager at Oxxius
Phodé has been collaborating with CBI/CRCA for the past 10 years. Over time, we have built a strong relationship of mutual trust with researchers Bruno Guiard and Lionel Mouledous. We have entrusted them with numerous studies on murine models to explore the effects and mechanisms of action of our aromatic formulations. As part of this collaboration, we had the opportunity and great satisfaction of co-publishing high-quality research findings in 2020. Building on this strong partnership, since 2022, we have entrusted them with the joint scientific supervision of a CIFRE doctoral thesis. Our PhD student, Clémence Viguier, has been fully integrated into the research team, further strengthening our collaborative efforts.
Virginie NOIROT, Head of Research Service, Phodé
ReST Therapeutics has decided to collaborate with three Toulouse-based laboratories (CBI-CRCA, IPBS and LHFA) as part of a CNRS LabCom initiative to develop translational research programs targeting the therapeutic potential of the NMDA receptor family for glutamate. Each of these laboratories brings essential expertise to ensure the success of this joint research effort : CBI-CRCA will handle in vivo biology, IPBS will focus for in vitro biology and LHFA will contribute to the chemistry aspects. I am confident that this collaboration will be highly fruitful and will fully meet our objectives.
Gilles RUBINSTENN, CEO ReST Therapeutics