Neural Circuit Development

We study how neural circuits are assembled during development, and how changes in neuronal circuity wiring impinge on neuronal function and behavior when development goes wrong.

Brain function relies on the communication between millions of neurons comprising numerous subtypes, which are precisely connected in discrete networks where each is devoted to specific tasks.

We use the fruit fly Drosophila melanogaster visual system as a model to understand the gene regulation, molecular and cellular mechanisms that regulate brain wiring, from development to circuit function.

We foresee that insights from our research will inform real-world translation applications, including the induction of stem cells to differentiate into specific neuronal types, potentially advancing cell replacement therapy.