Façonnage des motifs chromatiniens

Présentation

Projets

Genome-wide chromatin patterns

Epigenetic circuits in living cells

Single-molecule chromatin biophysics

Publications

• Arnould C, Rocher V, Saur F, Bader AS, Muzzopappa F, Collins S, Lesage E, Le Bozec B, Puget N, Clouaire T, Mangeat T, Mourad R, Ahituv N, Noordermeer D, Erdel F, Bushell M, Marnef A, Legube G..
  Chromatin compartmentalization regulates the response to DNA damage
  Nature
  2023 Oct
• Dolde U, Muzzopappa F, Delesalle C, Neveu J, Erdel F, Vert G.
  LEAFY homeostasis is regulated via ubiquitin-dependent degradation and sequestration in cytoplasmic condensates
  iScience 26: 106880
  2023 May
• Erdel F.
  Phase transitions in heterochromatin organization
  Curr Opin Struct Biol 80: 102597
  2023 Apr
• Muzzopappa F, Hummert J, Anfossi M, Tashev SA, Herten DP, Erdel F.
  Detecting and quantifying liquid-liquid phase separation in living cells by model-free calibrated half-bleaching
  Nature Communications 13: 7787
  2022 Dec
• Muzzopappa F, Hertzog M, Erdel F..
  DNA length tunes the fluidity of DNA-based condensates.
  Biophys J 120: 1-13
  2021 Feb

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Financements

             

Anciens membres

Étudiant.e.s en Master:

2019 - Elisabeth Schweigert (ERASMUS, Allemagne)

2020 - Antoine Solnais (M2 Gènes, Cellules & Développement)

2021 - Andressa Arabe Alves (M1 Biotechnologies : Bio-Ingénierie santé)

2023 - Gaëlle Lescalet (M2 Biologie Structurale et Génomique)

2023 - Laura Glepin (M2 Biologie-Santé)

 

Étudiant.e.s en License:

2023 - Sarah Mialet (L3 BioMIP)