Agenda

Flavio Donato (University of Basel, Switzerland)
NEUROBIOLOGY séminaire public
Titre : Divergent Recruitment of Developmentally-Defined Neuronal Ensembles Supports Memory Dynamics
12:15
4R4-RDC | Salle Conférence (182 pers.)

Memories are dynamic constructs whose properties change with time and experience. The biological mechanisms underpinning these dynamics remain elusive, particularly concerning how shifts in the composition of memory-encoding neuronal ensembles (“representational drift”) influence a memory properties’ evolution over time. By leveraging a developmental approach to target distinct subpopulations of principal neurons, we show that memory encoding results in the concurrent establishment of multiple memory traces in the mouse hippocampus. Two of these traces are instantiated in subpopulations of early- and late-born neurons and follow distinct reactivation trajectories post-encoding. Notably, the divergent recruitment of these subpopulations underpins memory ensembles’ gradual reorganization, and modulates memory persistence and plasticity across multiple learning episodes. Thus, we reveal profound and intricate relationships between ensemble dynamics and memories’ progression over time.

Gaia Novarino Institute of Science and Technology Austria
RNA séminaire public
Titre : “Studying the brain through the lens of human disorders”
11:00
4R4-RDC | Salle Conférence (182 pers.)

Sulov SAHA CBI-MCD- DAVY
Défense HDR/PhD
Titre : «ROLE OF ONE-CARBON METABOLISM IN NEOCORTEX DEVELOPMENT»
14:00
4R4-RDC | Salle Conférence (182 pers.)

RNA séminaire interne
Titre : RNA organisation
10:45
IBCG | Salle Conférence (100 pers.)

Andaine Seguin Centre for Anthropobiology and Genomics of Toulouse
CBI séminaire public
Titre : " An ancient DNA perspective on our human past
11:00
4R4-RDC | Salle Conférence (182 pers.)

Didier Trouche & Anna Mattout Team Trouche &Team Di Stefano / Mattout
RNA séminaire interne
Titre : “Genome wide CRISPR Cas9 screenings following cell sorting and for synthetic lethal genes” “ Lamin Mutant and Chromatin Organisation in a Muscular Dystrophy model”
14:00
IBCG | Salle Conférence (100 pers.)

CODE séminaire public
Titre : Séminaire PICS CODE
15:30
IBCG | Salle Conférence (100 pers.)