Genetic recombination and the cell cycle

François Cornet

Directeur de Recherche, CNRS
05 61 33 59 84

Team members

  • Bao Ton-Hoang
  • Estelle Brendon
  • Philippe Rousseau
  Technical staff
  • Luu Le Phan Thai
  • Carine Pagès


We are studying the global organization of bacterial genomes and its dynamics during the cell cycle and evolution by horizontal gene transfer. Using Escherichia coli as a model organism and a multi-scale approach involving biochemistry, biophysics, molecular genetics and cell biology, we put emphasis on the last steps of chromosome segregation and their integration with the cell cycle and cell division. We also investigate how the molecular machines involved in late segregation are domesticated by mobile genetic elements for their integration as bona fide parts of their host genome.


Genesis and maintenance of bacterial chromosomes

Internal control of the Xer recombination machine


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Université Paul Sabatier
118 Route de Narbonne

31062 TOULOUSE Cedex

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