Stem cells and development (STADE)

Alice Davy

Cedric Polesello


DR CNRS
05 61 55 75 51

CR CNRS
05 61 55 60 97

Presentation

Coordinators : Alice Davy – Cédric Polesello

 

The STADE (STem cell And DEvelopment) research programme aims to understand the fundamental processes by which cells acquire the right fate and location to form functional organs and organism.

The two common broad and intersecting scientific questions that are presently addressed in the program are:

  1. Which mechanisms maintain stem/progenitor/germ cells or, conversely, drive them to a specific differentiated state?
  2. How do tissues/organs acquire their shape and patterns during development?

These questions are studied from different angles and viewpoints: intrinsic (genetics, epigenetics), extrinsic (environmental, systemic, mechanics), at different scales (molecules, cells, organoids, tissues), using a large panel of animal models (Drosophila, zebrafish, Xenopus, mouse, birds) or in vitro models (primary cells, tissue explants).

 

Institute

Université Paul Sabatier
118 Route de Narbonne

31062 TOULOUSE Cedex
France

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