Proteostasis networks and translational control in bacteria

Pierre Genevaux

CR CNRS
05 61 33 59 73

LMGM

Researcher

Technical staff

Master student

Xu X, Usher B, Gutierrez C, Barriot R, Arrowsmith TJ, Han X, Redder P, Neyrolles O, Blower TR, Genevaux P..
MenT nucleotidyltransferase toxins extend tRNA acceptor stems and can be inhibited by asymmetrical antitoxin binding
Nat Commun.
2023 Aug 14(1):4644. doi: 10.1038/s41467-023-40264-3. PMID: 37591829
Mansour M, Giudice E, Xu X, Akarsu H, Bordes P, Guillet V, Bigot DJ, Slama N, D'urso G, Chat S, Redder P, Falquet L, Mourey L, Gillet R, Genevaux P.
Substrate recognition and cryo-EM structure of the ribosome-bound TAC toxin of Mycobacterium tuberculosis
Nature Communications
2022 May
Zuily L, Lahrach N, Fassler R, Genest O, Faller P, Sénèque O, Denis Y, Castanié-Cornet MP, Genevaux P, Jakob U, Reichmann D, Giudici-Orticoni MT, Ilbert M..
Copper Induces Protein Aggregation, a Toxic Process Compensated by Molecular Chaperones
mBio.
2022 Apr 26;13(2):e0325121. doi: 10.1128/mbio.03251-21. PMID: 35289645;
Zhao L, Castanié-Cornet MP, Kumar S, Genevaux P, Hayer-Hartl M, Hartl FU..
Bacterial RF3 senses chaperone function in co-translational folding
Mol. Cell.
2021 Jun S1097-2765(21)00400-7. doi: 10.1016/j.molcel.2021.05.016. PMID: 34107307
Bordes P, Genevaux P..
Control of Toxin-Antitoxin Systems by Proteases in Mycobacterium Tuberculosis
Front. Mol. Biosci.
2021 May 8:691399. doi: 10.3389/fmolb.2021.691399. eCollection 2021. PMID: 34079824 (Review)