Proteostasis networks and translational control in bacteria
Pierre Genevaux
CR CNRS
05 61 33 59 73
Team members
LMGM- Patricia Bordes
- Marie-Pierre Castanié-Cornet
- Michele Coddeville
- Come Stellio
- Xibing Xu
- Xue Han
- Ayako Yamakawa
- Ines Noureddine
Researcher Technical staff Master student --
Presentation

Publications
- Xu X, Usher B, Gutierrez C, Barriot R, Arrowsmith TJ, Han X, Redder P, Neyrolles O, Blower TR, Genevaux P..
MenT nucleotidyltransferase toxins extend tRNA acceptor stems and can be inhibited by asymmetrical antitoxin binding
Nat Commun.
2023 Aug 14(1):4644. doi: 10.1038/s41467-023-40264-3. PMID: 37591829 - Mansour M, Giudice E, Xu X, Akarsu H, Bordes P, Guillet V, Bigot DJ, Slama N, D'urso G, Chat S, Redder P, Falquet L, Mourey L, Gillet R, Genevaux P.
Substrate recognition and cryo-EM structure of the ribosome-bound TAC toxin of Mycobacterium tuberculosis
Nature Communications
2022 May - Zuily L, Lahrach N, Fassler R, Genest O, Faller P, Sénèque O, Denis Y, Castanié-Cornet MP, Genevaux P, Jakob U, Reichmann D, Giudici-Orticoni MT, Ilbert M..
Copper Induces Protein Aggregation, a Toxic Process Compensated by Molecular Chaperones
mBio.
2022 Apr 26;13(2):e0325121. doi: 10.1128/mbio.03251-21. PMID: 35289645; - Zhao L, Castanié-Cornet MP, Kumar S, Genevaux P, Hayer-Hartl M, Hartl FU..
Bacterial RF3 senses chaperone function in co-translational folding
Mol. Cell.
2021 Jun S1097-2765(21)00400-7. doi: 10.1016/j.molcel.2021.05.016. PMID: 34107307 - Bordes P, Genevaux P..
Control of Toxin-Antitoxin Systems by Proteases in Mycobacterium Tuberculosis
Front. Mol. Biosci.
2021 May 8:691399. doi: 10.3389/fmolb.2021.691399. eCollection 2021. PMID: 34079824 (Review)
View all publications
Funding
Alumni
- Yiming Cai
- Moïse Mansour
- Anne-Marie Cirinesi
- Olivier Fayet
- Marie-Françoise Prère
- Donna Joe Bigot
- Sarah Ayala
- Ola Al-fawares
- Pauline Texier
- Nawel Slama
- Ambre Sala
- Frédéric Angles
- Nicolas Bruel
- Elsa Perrody
- Samer Sakr