Molecular Chaperone Networks

Pierre Genevaux

CR CNRS
05 61 33 58 73

Team members

  Researcher
  • Patricia Bordes
  • Pierre Genevaux
  Associate professor
  • Marie-Pierre Castanié-Cornet
  Technical staff
  • Michèle Coddeville
  Postdoctoral fellow
  • Xibing Xu
  PhD student
  • Come Stellio
  • Xue Han

Thèmes de recherche

    Presentation

    chaperon-project

    The Molecular Chaperone Networks research group at the Laboratory of Microbiology and Molecular genetics (LMGM-CBI) mainly focuses on the biology of molecular chaperone machines in bacteria. Genetics, molecular biology and biochemistry technics are used to identify new molecular chaperone functions and to pin point key interplay between major chaperones, such as DnaK/HSP70, DnaJ/HSP40, GroEL/HSP60, Trigger Factor or SecB, and other bacterial stress proteins, including Toxin-Antitoxin systems (see Figure). More recently, we have focused on SecB-like molecular chaperones in the human pathogen M. tuberculosis and revealed for the first time the control of a stress-responsive Toxin-Antitoxin system by molecular chaperones. 

    Publications

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    Funding

               

    Alumni

    Moïse Mansour
    Olivier Fayet
    Marie-Françoise Prère
    Donna Joe Bigot
    Sarah Ayala
    Ola Al-fawares
    Pauline Texier
    Nawel Slama
    Ambre Sala
    Frédéric Angles
    Nicolas Bruel
    Elsa Perrody

     

    Institute

    Université Paul Sabatier
    118 Route de Narbonne

    31062 TOULOUSE Cedex
    France

    Annuaire général