Our team is interested in the role of chromatin modifications and the enzymes that regulate them in the control of mammalian cell proliferation and genetic stability. Our goal is to understand the molecular basis of the establishment of genetic programs associated with cell proliferation or anti-proliferative processes (terminal differentiation, senescence) by chromatin modifiers. We also study the involvement of these enzymes in genetic stability, focusing on DNA damage repair.
For more information, please consult the details of each of the team's projects ...
The team "Chromatin and Cellular Proliferation" is directed since its creation in 2000 by Dr Didier Trouche.
From 2000 to 2007, it was part of the LBME (Laboratory of Molecular Biology of Eukaryotes, CNRS-UPS UMR 5099).
In January 2007, the team joined the LBCMCP (Laboratory of Cellular and Molecular Biology of Proliferation Control, CNRS-UPS UMR 5088).
From 2011 to 2020, Didier Trouche was the director of the LBCMCP and, from 2016 to 2020, the director of the Center for Integrative Biology (CBI) of Toulouse with Pierre-Emmanuel Gleizes (Director of the LBME) as deputy.
The team is now part of the Center for Integrative Biology (CBI, CNRS-UPS FR3743) to which it belongs as a team attached to the Molecular, Cellular and Developmental Biology unit (MCD, CNRS-UPS UMR5077).
The laboratory is located on the campus of the University Toulouse III - Paul Sabatier, and housed in the building 4R4. It is also part of the Federation of Research in Biology of Toulouse (FRBT).
|Post-doctoral fellows||Technical or administrative staff||PhD Students||Students (except thesis)|
|Gaëlle LEGUBE||Laurent MASSIP||Sébastien BRIOIS||Sandrine TYTECA||Julien DURAND|
|Virginie CHARASSON||Assala LAAMA||Sabine PINEL||Pierre CARON||Lucie BARON|
|Marie VANDROMME||Muriel QUARANTA-NICAISE||Lise MATERRA||Cécile COIFFAIT|
|Marion AGUIRREBENGOA||Laure VERRIER||Rémi BOUDOU|
|Solène GAILLARD||Céline COURILLEAU||Clémence RIVES|
|Kader SALIFOU||Paul DUCHESNE|
|Sandra LAZORTHES||Caroline LEONI|
|Maharshi K DEB||Natacha PONSOLLE|
|Gemael TATY-TATY||Djihane ABDESSELAM|