Teams
Team publications Trouche
Small Interfering RNAs Targeting a Chromatin-Associated RNA Induce Its Transcriptional Silencing in Human Cells
Mol Cell Biol 42(12):e0027122
2022 Dec
RNA polymerase II speed: a key player in controlling and adapting transcriptome composition
EMBO J.
2021 Aug 40(15):e105740. doi:10.15252/embj.2020105740
Cytolethal Distending Toxin Promotes Replicative Stress Leading to Genetic Instability Transmitted to Daughter Cells
Front Cell Dev Biol.
2021 May 9:656795. doi:10.3389/fcell.2021.656795
KDM5A and KDM5B histone-demethylases contribute to HU-induced replication stress response and tolerance
Biol Open.
2021 May 10(5):bio057729. doi: 10.1242/bio.057729
Circular ANRIL isoforms switch from repressors to activators of p15/CDKN2B expression during RAF1 oncogene-induced senescence
RNA Biol.
2021 Mar 18(3):404-420. doi:10.1080/15476286.2020
Chromatin Dynamics in Intestinal Epithelial Homeostasis: A Paradigm of Cell Fate Determination versus Cell Plasticity
Stem Cell Rev Rep
2020 Dec 16(6):1062-1080. doi:10.1007/s12015-020-10055-0
JMJD6 participates in the maintenance of ribosomal DNA integrity in response to DNA damage
PLoS Genet
2020 Jun 16(6):e1008511. doi: 10.1371/journal.pgen.1008511
Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation.
Elife
2020 Feb 28;9. doi: 10.7554/eLife.53375
The H2A.Z histone variant integrates Wnt signaling in intestinal epithelial homeostasis
Nat Commun
2019 Apr 10(1):1827. doi:10.1038/s41467-019-09899-z
Methods for In Vivo Functional Studies of Chromatin-Modifying Enzymes in Early Steps of Colon Carcinogenesis.
In: Colorectal Cancer. Methods in Molecular Biology
2018 Mar Beaulieu JF (eds) Humana Press, New York, NY 1765:79-85.
Control of gene expression in senescence through transcriptional read-through of convergent protein-coding genes
Cell Reports
2017 Nov 21(9):2433-2446.
Control of genetic stability by a new heterochromatin compaction pathway involving the Tip60 histone acetyltransferase.
Mol Biol Cell.
2016 Jan 27(4):599-607
The histone demethylase JMJD2A/KDM4A links ribosomal RNA transcription to nutrients and growth factors availability.
Nat Commun.
2016 Jan 7:10174
Control of alternative end joining by the chromatin remodeler p400 ATPase.
Nucleic Acids Res.
2015 Nov 44(4):1657-68
A vlincRNA participates in senescence maintenance by relieving H2AZ-mediated repression at the INK4 locus.
Nat Commun.
2015 Jan 6:5971
Interplay between chromatin-modifying enzymes controls colon cancer progression through Wnt signaling.
Hum Mol Genet.
2014 Apr 23(8):2120-31
Quantifying DNA double-strand breaks induced by site-specific endonucleases in living cells by ligation-mediated purification.
Nat Protoc.
2014 Mar 9(3):517-28
H2A.Z depletion impairs proliferation and viability but not DNA double-strand breaks repair in human immortalized and tumoral cell lines.
Cell Cycle
2014 Jan 13(3):399-407
The chromatin remodeler p400 ATPase facilitates Rad51-mediated repair of DNA double-strand breaks.
J Cell Biol.
2012 Dec 199(7):1067-81
Histone demethylases in chromatin cross-talks.
Biol Cell.
2011 Aug 103(8):381-401. Review
A new isoform of the histone demethylase JMJD2A/KDM4A is required for skeletal muscle differentiation.
PLoS Genet.
2011 Jun 7(6):e1001390
The E1A-associated p400 protein modulates cell fate decisions by the regulation of ROS homeostasis.
PLoS Genet.
2010 Jun 6(6):e1000983
High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome.
EMBO J.
2010 Apr 29(8):1446-57
Physical interaction between the histone acetyl transferase Tip60 and the DNA double-strand breaks sensor MRN complex.
Biochem J.
2010 Feb 426(3):365-71