Cardiac Valve Regeneration

One of the main cardiovascular tissues affected by disease is the cardiac valve which is responsible to maintain the unidirectional blood flow within the heart.

We have established a model to study cardiac valve regeneration in zebrafish and understand how tissues can be rebuild in a beating heart.

In this project we use this genetic model to unravel the regenerative process, with a particular focus on clarifying how cell heterogeneity contributes to promoting regeneration.

Funding