Control of cancer invasion by the novel PKCtheta

Intervenants

  • Xiaobo Wang
  • Karine Belguise
  • Liwen Gan
  • Hao Li
  • Bing Liu
  • Kevin Mouysset
  • Ningwei Sun
  • Ye Zhang
  • Sijia Zhou

Currently, there is no efficient targeted therapy that can prevent the metastatic dissemination of triple-negative breast cancer (TNBC). Our recent work identified PKCtheta as a potential new marker of TNBC and as a strong inducer of cancer invasion. PKCtheta is well known for its role in the immune system. However, the link between PKCtheta and cancer is extremely limited. Our project is to understand how PKCtheta controls the cancer invasion. To determine the detailed mechanism of this control, we are using cancer cells and mouse models.

Funding

Other funding : ATIP-Avenir

Université Paul Sabatier
118 Route de Narbonne

31062 TOULOUSE Cedex
France


05 61 33 58 00

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