High-throughput screening

Zebrafish are a valuable model for large-scale small compound screening by combining the advantages of in vitro screens (e.g. high-throughput, low-cost) in an in vivo system.

In this project we will use a Vertebrate Automated Screening Technology platform coupled with a spinning-disk confocal microscope (VAST-SDCM) to perform a fast, high-resolution screen of cardiovascular phenotypes in zebrafish larvae.

Funding