Chromatin dynamics


  • Olivier Cuvier
  • Charlène Perrois
  • David Depierre
  • Olivier Fosseprez
  • Nicolas Chanard

Our research goals aim at tackling the mechanisms and factors that impacts processes such as transcription/replication through chromatin folding. We focus our work on such structure-function relationships and analyze the potent roles of factors including histone modifiers, SMCs, insulator proteins, together with the ‘pausing’ of RNAPol2, or with the activation of DNA replication origins. One main goal is to understand how such factors help to avoid fork collisions, a major source of genomic instability.




Université Paul Sabatier
118 Route de Narbonne

31062 TOULOUSE Cedex

Annuaire général