Visualization of chromatin loops in vivo

It is well established that epigenetic gene regulation is regulated by chromatin structure. However, the biophysical properties of chromatin in vivo are still poorly understood. Here, we propose to elucidate the interplay between chromatin properties and transcription regulation focusing on chromatin loops. . We will explore the properties of   chromosomes in a consortium involving biophysicists, geneticists and cell biologists.

This work is a collaboratif effort with teams of  K. Bystricky (CBI), A. Bancaud (LAAS- Toulouse) and C. Zimmer (Institut Pasteur, Paris)

Funding